Chronotherapy refers to treatments for depression, mania, or both, that focus on changing sleep and wakefulness patterns. This blog post provides an update of this important area. Background The International Society of Bipolar Disorders (ISBD) task force on chronobiology and chronotherapy published a comprehensive review of chronotherapy techniques and their effectiveness in bipolar disorder in 2019. This article summarizes the …
Predicting Lithium Response
Lithium is usually considered the most effective treatment for bipolar disorder. However, at least 30% of lithium-treated patients do not have a clinically significant response; and only 30% have a long-lasting full response. Since close laboratory monitoring is required, and adverse effects are not uncommon, identifying predictors of lithium response is highly desirable. In this largest-ever study of lithium recipients …
Lithium Associated Hypothyroidism May Be Reversible
People who develop hypothyroidism while using the mood stabilizer lithium may return to normal thyroid function after the drug is discontinued, according to a study in the Journal of Psychopharmacology. Hypothyroidism—a condition in which the thyroid gland does not produce enough thyroid hormone—has long been known to be associated with the use of lithium. Recent studies have clarified the nature of this association. …
Specialty Care for Bipolar Matters
Bob Post (one of the most eminent psychiatrists of our time) published a passionate article in the March 2018 edition of the Journal of the American Medical Association in support of the importance of specialty care for bipolar disorder. Of course, we couldn’t agree more. That is one of the reasons we founded the clinic. We saw that specialty care …
Brain Training for Bipolar
Cognitive problems are the rule rather than the exception for people with bipolar disorder and so the idea of brain training for bipolar is an attractive one. There are a number of commercially available brain training courses. Probably one of the most comprehensive was developed by a company called Posit Science. Its current flagship product is a subscription-based online program …
Bipolar 101 An Online Course
Bipolar 101, an online course hosted by Gateway Psychiatric begins March 17, 2017: Bipolar 101 – The Basics and Beyond. The class is based on the acclaimed Barcelona Bipolar Disorders Program. Bipolar 101 – An online course will cover topics such as: It will be taught by Dr. Peter Forster and Gina Gregory, and will have an interactive format with plenty of …
Long Acting Injectable Aripiprazole for Bipolar
Long acting injectable aripiprazole for bipolar one patients has been shown to significantly reduce the risk of a recurrence of a mood episode in a 52 week placebo controlled clinical trial. Poor adherence to treatment is a significant problem in patients with bipolar disorder, putting patients at increased risk of recurrence of mood episodes, hospitalization, and suicide. One other study …
Atypical Antipsychotics with Mood Stabilizers
Many people with bipolar receive atypical antipsychotics with mood stabilizers. As in many areas of medicine, we have relatively little data about longer-term outcomes when people receive this combination. If an atypical antipsychotic is added to a mood stabilizer to control a manic episode, how long should that combination be prescribed? A recent study conducted by the Canadian Mood and …
UCSF Bipolar Education Group Starts Again
Dr. Descartes Li, an expert in Bipolar Disorder at UCSF runs an excellent 8 session program for people with bipolar who are interested in learning more. Here is the latest information about the group which starts at the end of February. The UCSF bipolar psychoeducational group starts on February 27, 2017. It runs for 8 sessions, Mondays 12pm to 115pm. …
Pregnancy and Bipolar
Pregnancy Outcomes in Women with Bipolar Disorder A recent review of the topic of bipolar and pregnancy from the MGH Center For Women’s Mental Health on November 14, 2016 sparked us to write this post. When talking with a bipolar woman contemplating pregnancy there are two considerations: what additional risks to the unborn child are created by taking psychiatric medication and what risks exist …