Below you'll find a list of all posts that have been categorized as “Treatments of Depression”
Depression is a common mental illness that affects millions of people worldwide. It can cause a wide range of symptoms, including sadness, fatigue, difficulty concentrating, and changes in appetite. Depression can also have a significant impact on a person’s quality of life. One way to treat depression is with medication. Antidepressants are a type of medication that can help to …
For decades, the serotonin theory of depression has been the prevailing explanation for the disorder. The theory holds that depression is caused by low levels of serotonin, a neurotransmitter that plays a role in mood regulation. This theory has led to the development of many popular antidepressants, which work by increasing serotonin levels in the brain. However, a new study …
Recently there has been a lot of interest in using psilocybin as a treatment for depression, anxiety and alcohol use disorder. We certainly need more safe and effective treatments. It may be worth considering where we are in the evaluation of these agents. Right now there is a growing literature supporting the potential value of these agents, but there is …
Gateway Psychiatric just joined the Psychedelic Medicine Association. This membership is a continuation of our longstanding interest in alternative treatments for depression. I have been working with Bay Psychiatric Associates and Roberto Estrada for nearly five years providing ketamine infusion and now nasal esketamine to patients with treatment resistant depression. This followed attending the 2017 Ketamine Conference which was held …
One of the questions that has bedevilled clinicians ever since the introduction of the first SSRI (Prozac, fluoxetine) is whether there is any relationship between SSRI doses and effectiveness. In other words, do higher doses result in greater effectiveness. I can recall about 20 years ago reading the first clinical trial looking at this question. It was an article published …
We have several other posts on this topic which trace the evolution of our thinking about the risks of using antidepressants during pregnancy. Generally, the data continues to support our view that the risks of depression during pregnancy, both in terms of effects on the mother and effects on the child, usually outweigh the risks of antidepressant use. Another large …
Psychotherapies — particularly cognitive-behavioral approaches used as adjunctive treatments — can play a critical role in helping people with a history of depression avoid relapse. For many people, major depression is a chronic illness. Even when they are no longer depressed, people who have had several episodes of depression have to be concerned about a significant risk of a recurrence …
We have been eagerly awaiting the results of controlled studies of psilocybin treatment of depression (used along with psychotherapy). A large multi-center study is still recruiting participants. Meanwhile a great deal of interest in this topic has been stirred up by Michael Pollan and his book How to Change Your Mind. But clinicians have had very little solid science upon …
Boadie Dunlop, M.D., M.S., and Helen Mayberg, M.D., both of Emory University School of Medicine, and colleagues assessed resting-state functional connectivity between the subcallosal cingulate cortex (SCC) and three other brain regions—the dorsal midbrain, the ventrolateral prefrontal cortex and anterior insula, and the ventromedial prefrontal cortex—in 122 patients with depression. The patients were then randomized to 12 weeks of cognitive-behavioral …
Why do depressed people make choices that are unlikely to be rewarded. And why aren’t they willing to make choices that are likely to be rewarded. In fact, why are depressed people less likely than people who are not depressed to choose to take an antidepressant, or begin psychotherapy, or follow the advice of a therapist? A meta-analysis of many …
